Drug Interaction List The Diabetic Patient Should Aware of

Diabetic patients should aware the use of different type of medicine that they are using with their antidiabetic therapy.There are different types of medicine that a diabetic patient can use such as the antihypertensive drug, lipid lowering agent, antiplatelet agent and so on. These all medication might continue with their antidiabetic treatment  so patients should be aware  of  the use of these types of drug.

 

An adverse drug reaction and drug -drug interaction are very common when you use multiple drugs at a time .This will impact on  the effectiveness of  drug and sometimes alter their mechanism.Today I will discuss some major drug-drug and drug-disease  interaction  which a Diabetic patient should know .

Sulfonyl Urea and alcohol : The first generation sulfonylurea is  Chlorpropamide may cause facial flushing reaction when it is ingested together with alcohol .

 Metformin : Metformin should be always taken after the meal  to overcome the gastrointestinal side effect  .Metformin cause vit B12 deficiency anemia so oral or injectable  Vit B12 should be used to overcome this . Procainamide, digoxin, quinidine, trimethoprim, and vancomycin which are cationic in nature and have the serious interaction with Metformin .

Thiazolidinediones:No significant drug-drug interaction has been reported  for Thiazolidinediones.Although they have significant drug-disease interaction which may result in peripheral edema ,rarely pulmonary edema or heart failure .They also increase the absorption of Na ion from kidney  and cause the systemic vascular resistance .

α-Glucosidase inhibitors : Acarbose and  miglitol which are α-Glucosidase inhibitors reduce the absorbance of the digoxin .On the other, hand several cases has been reported which increase the metabolism of the warfarin .These group of medicine is contraindicated with the certain gastrointestinal disorder like short bowel syndrome, Crohn's disease etc .